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Updated: Jul 11, 2025

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通过有机阴离子载体聚1C1 (OATP1C1) 向质细胞 - - 使用l-氨酸衍生的产物药物

Arun Kumar Tonduru1, Seyed Hamed Maljaei1, Santosh Kumar Adla1

  • 1School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland.

Journal of medicinal chemistry
|November 6, 2023
PubMed
概括

研究人员使用甲状腺激素甲状腺素 (T4) 开发了新的前药物,以通过OATP1C1载体增强抗炎药物通过OATP1C1载体向大脑质细胞的输送. 基于T4的前期药物显示出优异的吸收和结合,这表明改善大脑药物输送的潜力.

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