处方阿片类药物剂量减少和潜在的不良事件:在美国多个卫生系统的多站点观察队列研究

Verena E Metz1, G Thomas Ray2, Vanessa Palzes2

  • 1Kaiser Permanente Northern California, Division of Research, Center for Addiction and Mental Health Research, Oakland, CA, USA. verena.e.metz@kp.org.

概括

美国的阿片类药物剂量减少与不良事件有关. 较大的减少 (30-100%) 增加了急诊室访问,过量服用和死亡的风险,而较小的减少 (15-30%) 增加了急诊室访问的几率.

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