在复发性复发性多发性硬化症中的执行功能
M Rosa Elosúa1, Noelia Villadangos1,2
1Departamento de Psicología Básica I, UNED, Madrid, Spain.
Applied neuropsychology. Adult
|November 6, 2023
概括
多发性硬化症 (MS) 患者表现出工作记忆受损,特别是注意力分裂和更新功能,影响日常生活. 在注意力转移或抑制方面没有观察到缺陷.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 临床神经学 临床神经学
背景情况:
- 关于复发性缓解性多发性硬化症 (MS) 中的执行功能缺陷存在不一致的发现.
- 工作记忆和执行功能对于日常活动至关重要,可能会受到MS的影响.
研究的目的:
- 研究MS患者的执行功能,包括注意力分裂,更新,注意力转移和抑制.
- 为了比较患有MS的个体与健康对照者之间的认知表现.
主要方法:
- 使用双任务范式,N-Back任务,Trail Making Test (TMT) 和Stroop测试来评估特定的执行功能.
- 包括24名患有多发性硬化症的参与者和24名年龄和教育相匹配的健康对照 (18-59岁).
主要成果:
- 与对照人群相比,患有多发性硬化症的个体在分散注意力和更新方面表现出显著的损伤.
- 在MS组的四个执行职能中注意到了绩效的变化.
- 在注意力转移或抑制方面没有发现显著的缺陷.
结论:
- 认知需求加剧了MS患者的注意力分裂和更新缺陷.
- 这些执行功能障碍对MS患者的日常功能有着显著的临床影响.
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