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Updated: Jul 11, 2025

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超增强剂活动的SOX2依赖调节的分子基础

Wanki Yoo1, Yi Wei Song1, Jihyun Kim2

  • 1Department of Precision Medicine, Graduate School of Basic Medical Science (GSBMS), Institute for Antimicrobial Resistance Research and Therapeutics, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea.

Nucleic acids research
|November 6, 2023
PubMed
概括

像SOX2这样的先驱转录因子 (TFs) 通过在超级增强剂 (SE) 上形成凝结物来驱动干和癌症. 这项研究揭示了SOX2和p300合作通过SEs的转录凝聚调节基因表达.

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