用智能手机应用程序和isCGM进行生活方式干预,用于2型糖尿病高风险人群:随机试验
Masaru Kitazawa1, Yasunaga Takeda1, Mariko Hatta1
1Department of Hematology, Endocrinology, and Metabolism, Niigata University Faculty of Medicine, Niigata 951-8510, Japan.
The Journal of clinical endocrinology and metabolism
|November 6, 2023
概括
一个带有持续血糖监测的智能手机应用程序改善了血糖控制,并降低了2型糖尿病高风险人群的体重. 这种数字干预提供了一种可扩展的糖尿病预防方法.
科学领域:
- 内分泌学 在内分泌学.
- 数字健康数字健康
- 预防医学 预防医学
背景情况:
- 传统的2型糖尿病预防计划对医疗保健提供者来说是资源密集型的.
- 数字健康解决方案正在成为生活方式干预的可扩展替代方案.
- 持续血糖监测 (CGM) 为个性化反提供客观数据.
研究的目的:
- 为了研究智能手机应用程序与间歇扫描的持续血糖监测 (isCGM) 结合,改善血糖控制和降低体重的有效性.
- 评估数字生活方式干预措施,尽量减少医疗保健提供者的负担.
主要方法:
- 一项为期12周的随机无盲试验,涉及患有糖尿病前期 (血红蛋白A1c5.6%-6.4%或禁食葡萄糖110-125 mg/dL) 和超重/肥胖 (BMI>23 kg/m2) 的参与者.
- 参与者被分配到使用智能手机应用程序和isCGM的干预组或对照组.
- 主要结局是血糖范围 (70-140毫克/分升) 的时间变化.
主要成果:
- 与对照组相比,干预组在血糖时间范围 (TIR) 中显著改善.
- 干预组的时间在范围以下显著增加 (血糖<70 mg/dL),BMI下降.
- 两组之间在时间超出范围时没有观察到显著差异.
结论:
- 使用智能手机应用程序和isCGM进行的生活方式干预,有效地提高了血糖控制,并促进了2型糖尿病风险人群的体重减轻.
- 这种数字方法表明了可扩展和提供者高效的糖尿病预防的潜力.
- 需要进一步的研究来证实对2型糖尿病发病率的长期影响.
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