Foxp3调节染色体结构的重组,以建立调节性T细胞身份

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Updated: Jul 11, 2025

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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Zhi Liu1,2, Dong-Sung Lee3,4, Yuqiong Liang2

  • 1Shanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Nature communications
|November 6, 2023
PubMed
概括

转录因子Foxp3对于建立调节性T细胞 (Treg) 特定的3D染色体结构至关重要. 这种组织对于Treg谱系的规范和免疫反应中的功能至关重要.

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