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相关概念视频

Anatomy of the Intestines01:23

Anatomy of the Intestines

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Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
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Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

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The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
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What is Monogastric Digestion?01:50

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The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
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Evolutionary Psychology01:20

Evolutionary Psychology

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Evolutionary psychology explores the origins of human behavior and mental processes by framing them within the context of natural selection, a theory famously propounded by Charles Darwin. This field asserts that many behaviors common across human societies — ranging from instinctive fear reactions to complex social interactions — arose as evolutionary adaptations. These adaptations enhanced the survival and reproductive success of our ancestors, thereby becoming embedded in the...
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Transduction01:16

Transduction

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Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome...
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Biodiversity and Human Values01:24

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Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
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相关实验视频

Updated: Jul 11, 2025

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
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人的肠道微生物群中的生态进化反.

Benjamin H Good1,2,3, Layton B Rosenfeld4

  • 1Department of Applied Physics, Stanford University, Stanford, CA, 94305, USA. bhgood@stanford.edu.

Nature communications
|November 6, 2023
PubMed
概括

人的肠道微生物组迅速发展,影响其社区结构. 这些进化转变对遥远的微生物产生影响,这表明当地的进化历史塑造了个性化医学的微生物组功能.

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科学领域:

  • 微生物组研究的研究.
  • 进化生物学是进化的生物学.
  • 社区生态学社区生态学

背景情况:

  • 人的肠道微生物群在与人类相关的时间尺度上演变.
  • 人们对微生物进化如何影响社区组成知之甚少.
  • 了解这些动态对于微生物组工程和个性化医学至关重要.

研究的目的:

  • 研究短期微生物进化与人类肠道生态结构之间的联系.
  • 为了确定微生物群中的进化变化是否会影响超越进化的物种之外的社区组成.
  • 探索驱动这些生态和进化反的潜在机制.

主要方法:

  • 对大量人类肠道转基因组的生态和进化分析.
  • 相关性分析将微生物进化与社区结构转变联系起来.
  • 资源竞争建模以模拟生态反.

主要成果:

  • 肠道微生物群的短期进化与其生态结构的变化密切相关.
  • 这些相关性涉及远距离相关的种类的波动,而不仅仅是进化的物种的扩张.
  • 在简单的资源竞争模型中出现了类似的生态和进化反.

结论:

  • 主体肠道微生物群的结构和功能可能是由其本地进化历史所塑造的.
  • 这些发现对个性化医学和微生物组工程有潜在的影响.
  • 微生物进化和社区生态在宿主中是紧密联系在一起的.