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Updated: Jul 11, 2025

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
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Induction and Assessment of Class Switch Recombination in Purified Murine B Cells

Published on: August 13, 2010

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sciCSR推断了B细胞状态过渡,并使用单细胞转录基因数据预测了类切换重组动态

Joseph C F Ng1, Guillem Montamat Garcia2, Alexander T Stewart3

  • 1Department of Structural and Molecular Biology, Division of Biosciences and Institute of Structural and Molecular Biology, University College London, London, UK. joseph.ng@ucl.ac.uk.

Nature methods
|November 6, 2023
PubMed
概括

本研究介绍了sciCSR,这是一种用于分析单细胞RNA测序数据的B细胞成熟和类交换重组 (CSR) 的计算工具. sciCSR准确地预测了B细胞受体同型分布,为免疫反应提供了新的见解.

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