在急性缺血性中风中心率动荡
Helena Stengl1,2,3, Ramanan Ganeshan1,2, Regina von Rennenberg1,2,4
1Department of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
European stroke journal
|November 7, 2023
概括
心率动荡 (HRT) 是自主心脏调节的标志物. 在急性缺血性中风患者中,严重异常的HRT与更大的残疾和心脏问题有关,但与死亡率无关.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 自主功能测试自主功能测试
背景情况:
- 心率动荡 (HRT) 是基于心电图的自主心脏调节标志物.
- HRT在心血管疾病中具有预后价值,但急性缺血性中风患者的数据有限.
研究的目的:
- 调查HRT在急性缺血性中风患者的预后价值.
- 评估HRT参数与临床结果之间的关联,包括功能性结果,死亡率,心房动和心肌纤维化.
主要方法:
- 在335名急性缺血性中风患者中,分析了Holter-ECG记录的HRT参数 (动开始和斜率).
- HRT被分为正常,异常或严重异常.
- 结果包括修改的兰金度量得分,1年死亡率,新的心房动和心脏MRI检测到的心肌纤维化.
主要成果:
- 严重异常的HRT与3个月后增加的残疾 (更高的mRS) (aOR:2.9) 和新的心房动 (aOR:3.5) 相关.
- 严重异常的HRT也与MRI检测到的心肌纤维化有关 (aOR:5.8).
- 没有发现HRT类别与1年死亡率之间有显著的关联;异常HRT与任何分析结果无关.
结论:
- 在急性缺血性中风患者中,严重异常的HRT与增加的残疾和心脏并发症有关.
- HRT可能有助于确定需要进一步监测心房动和心脏成像的患者.
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