结直肠癌和肠道微生物群的视觉分析:从2002年到2022年的文献计量分析
Dan Long1, Chenhan Mao2, Zhensheng Zhang3
1The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Medicine
|November 7, 2023
概括
对肠道微生物群 (GM) 和结直肠癌 (CRC) 的研究正在迅速扩大. 这种图书统计分析揭示了关键的研究趋势,包括特定细菌 (如Fusobacterium nucleatum) 的作用,以及对免疫反应和新疗法的新兴关注.
科学领域:
- 微生物学 微生物学
- 在瘤学瘤学.
- 生物信息学是一种生物信息学.
背景情况:
- 肠道微生物群 (GM) 越来越多地被认为在结直肠癌 (CRC) 发展中的关键作用.
- 尽管进行了广泛的研究,但对GM-CRC领域缺乏全面的文献统计概述.
研究的目的:
- 在过去二十年 (2002-2022) 进行肠道微生物群和结直肠癌研究的文献分析.
- 在这个跨学科领域确定研究热点,前沿和新兴趋势.
主要方法:
- 在科学网络核心集合数据库中搜索相关出版物.
- 利用CiteSpace和VOSviewer对国家,机构,作者,期刊和关键词进行科学度分析.
- 应用关键词的同时出现,集群和突发分析来识别趋势.
主要成果:
- 总共有2158个出版物被确定,显示了年度产量的显著增加.
- 中国和美国是主要的贡献者;确定了关键的作者和机构.
- 研究集群的重点是益生菌,炎症,分子机制和方法.
- 目前的热点包括Fusobacterium nucleatum和大肠杆菌;新兴的研究强调免疫反应和CRC治疗策略.
结论:
- 肠道微生物群和结直肠癌之间的关系仍然是一个充满活力和重要的研究领域.
- 未来的研究很可能会集中在CRC患者的微生物组成变化,潜在的分子机制以及益生菌和天然产品的治疗潜力上.
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