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Updated: Jul 11, 2025

Using Nicotine in a Silica-Exposed Mouse Model to Promote Lung Epithelial-Mesenchymal Transition
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尼古丁会影响人类呼吸道平滑肌细胞中的线粒体结构和功能

Niyati A Borkar1, Michael A Thompson1, Colleen M Bartman1

  • 1Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States.

American journal of physiology. Lung cellular and molecular physiology
|November 7, 2023
PubMed
概括

尼古丁暴露会通过破坏呼吸道光滑肌肉细胞中的线粒体而使喘恶化,特别是通过α7尼古丁乙胆受体 (α7nAChRs) 影响调节和能量产生. 这项研究揭示了线粒体是尼古丁的关键目标.

关键词:
喘 喘 是一种和是最重要的.裂变 - 聚变 - 核聚变线粒体中的线粒体.尼古丁胆固醇受体 尼古丁胆固醇受体

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