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[METTL3抑制剂STM2457通过调节小鼠的线粒体功能来改善与代谢功能障碍相关的脂肪肝疾病]

Y Gao1, P Wang1, S Lu1

  • 1Department of Clinical Laboratory Medicine, First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Medicine and Health Key Laboratory of Laboratory Medicine, Jinan 250014, China.

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
|November 7, 2023
PubMed
概括

甲基转移酶类3 (METTL3) 抑制剂STM2457有效治疗小鼠的代谢功能障碍相关的脂肪肝疾病 (MAFLD). 这种化合物减少肝脏脂肪,改善胰岛素敏感性,并保护线粒体免受损伤.

关键词:
在METTL3中,METTL3是METTL3的第一个类型.在 STM245757 中使用.m6A甲基化修改的方法与代谢功能障碍相关的脂肪肝疾病.线粒体中的线粒体.

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