[驾驶压力导向肺部保护性通风策略可减少COVID-19中恢复过来的患者手术后肺部并发症]
1Department of Anesthesiology, First Affiliated Hospital of Wannan Medical College, Wuhu 241000, China.
概括
以驱动压力为指导的肺保护性通风策略 (LPVS) 在最近从COVID-19中恢复过来的患者中显著减少了术后肺部并发症和低氧化,改善了手术内呼吸道管理.
科学领域:
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
背景情况:
- 从COVID-19中康复的患者可能会增加术后肺部并发症 (PPC) 的风险.
- 优化手术内呼吸道管理对于这个患者群体至关重要.
研究的目的:
- 评估由驱动压力指导的肺保护性通风策略 (LPVS) 在预防PPC的有效性.
- 为优化最近从COVID-19中恢复过来的患者在手术期间的呼吸系统管理.
主要方法:
- 最近从COVID-19中恢复过来的118名接受选择性非心脏手术的患者被随机分为LPVS和对照组.
- LPVS组接受了6毫升/公斤的潮体积,个性化PEEP和肺部再扩张;对照组接受了传统通风.
- 对比了PPC的发生率,低氧化和肺超声波得分.
主要成果:
- 与对照组相比,LPVS组的PPC发病率 (16.95%与35.59%) 和低氧血症 (15.25%与30.51%) 显著降低.
- 肺超声波得分在LPVS组显著较低 (5.31±1.07对比8.32±2.34).
- LPVS组的PEEP,气道压力和平原压力较高,但驱动压力和潮体积较低.
结论:
- 以驱动压力为指导的LPVS有效降低最近从COVID-19中恢复过来的患者的PPC和低氧血症.
- 这一策略改善了氧化,可以用来优化手术期间的呼吸管理.
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