在输管后的急性喉损伤中,粘膜微生物组的破坏
Ruth J Davis1, Meghan H Shilts2, Britton A Strickland3
1Department of Otolaryngology-HNS, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
概括
细菌感染在输管术后的急性喉损伤 (ALgI) 中很常见. 经常发现葡萄球菌和链球菌物种,支持向抗生素治疗,以改善患者的治疗结果.
科学领域:
- 微生物学 微生物学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 关键护理医学 关键护理医学
背景情况:
- 急性喉损伤 (ALgI) 可能发生在内内输管后.
- 了解ALgI中的微生物环境对于有效治疗至关重要.
- 异常性小结节狭窄症 (iSGS) 作为一个比较条件.
研究的目的:
- 在ALgI输管后患者的粘膜微生物转移的特征.
- 将ALgI中的微生物发现与iSGS和健康对照进行比较.
- 为了确定ALgI伤口中普遍存在的细菌物种.
主要方法:
- 横截面研究设计. 截面研究设计.
- 包括20名ALgI患者,20名iSGS患者和3名对照.
- 组织和粘膜培养物用于微生物分析.
主要成果:
- 在70%的ALgI患者中发现了阳性细菌培养,而在iSGS患者中发现了5%.
- 在对照组中没有观察到阳性培养.
- 葡萄球菌 (30%) 和链球菌 (25%) 是ALgI中最常见的分离物.
结论:
- 在化后的喉伤口中,细菌透率很高.
- 支持减少内管细菌的殖民化.
- 强调在早期ALgI干预中培养导向抗生素治疗的重要性.
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