未来不仅仅是光明:美国对脂肪肝疾病的定量化作用的演变
Arinc Ozturk1, Viksit Kumar1, Theodore T Pierce1
1From the Center for Ultrasound Research & Translation, Department of Radiology, Massachusetts General Hospital, 101 Merrimac St, 3rd Floor, 323G, Boston, MA 02114 (A.O., V.K., T.T.P., Q.L., M.B., P.G., S.S., Y.G., S.D., A.E.S.); Harvard Medical School, Boston, Mass (A.O., V.K., T.T.P, Q.L., A.E.S.); Departments of Medical Physics and Radiology, University of Wisconsin, Madison, Wis (I.R.M.); GE HealthCare, Milwaukee, Wis (M.W.); and Department of Radiology, University of Florida, Gainesville, Fla (J.R.G.).
超声波为评估非酒精性脂肪性肝病 (NAFLD) 提供了一种具有成本效益,可访问性和非侵入性的方法. 本综述探讨了用于诊断NAFLD的当前和新兴超声波技术,为肝脏活检提供了替代方案.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 医疗成像医学成像
- 诊断性的超声波检查
背景情况:
- 非酒精性脂肪肝 (NAFLD) 是肝脏相关疾病和死亡的重要原因.
- 肝脏活检是NAFLD的传统诊断标准,由于其侵入性,高成本和采样错误的可能性,它带来了挑战.
- 图像成像模式对于NAFLD的非侵入性评估至关重要,它提供了可量化的数据和差异诊断能力.
研究的目的:
- 审查基于超声波的技术的优点和局限性,以诊断非酒精性脂肪性肝病 (NAFLD).
- 讨论临床上可用的和实验性的超声波方法,用于肝脏组织的特征.
- 探索未来的应用和战略,以改善超声波在NAFLD管理中的作用.
主要方法:
- 对超声波 (美国) 技术的现有文献的综述,用于评估NAFLD的肝脏脂肪,纤维化和炎症.
- 讨论商业上可用的美国工具,如剪切波弹性学,多普勒光谱成像,衰减系数,肝鼻指数,声音速度和基于反射的估计.
- 探索使用频道和射频数据分析的新兴美国方法.
主要成果:
- 超声波 (美国) 是NAFLD评估的有希望的非侵入性工具,与MRI相比,它在成本,可用性和患者耐受性方面具有优势.
- 几种基于美国的评估肝纤维化,脂肪和炎症的方法已经在临床使用中,并获得了监管许可.
- 美国的实验技术显示出潜力,但需要进一步开发以获得广泛的临床应用.
结论:
- 超声波是一种有价值的非侵入性方法,用于诊断和监测非酒精性脂肪性肝病 (NAFLD).
- 当前和新兴的超声波技术为人口层面的NAFLD评估提供了肝脏活检的可行替代方案.
- 对超声波技术的持续研究和开发对于克服局限性并提高NAFLD的诊断准确性至关重要.
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