无冠状动脉的大动脉:一种罕见形的解剖学变体
Julie Karila-Cohen1, Daniela Laux2, Lucile Houyel2,3
1Medical and Surgical Unit of Congenital and Paediatric Cardiology, Reference Centre for Complex Congenital Heart Defects - M3C, University Hospital Necker-Enfants Malades, Paris, France. julie.karila-cohen@aphp.fr.
Pediatric cardiology
|November 7, 2023
概括
冠状动脉不能连接到大动脉的先天性心脏缺陷非常罕见. 这项研究详细介绍了四个独特的病例,包括冠状动脉几乎完全缺失,这挑战了目前对冠状动脉发育的理解.
科学领域:
- 心脏病学 心脏病学
- 发展生物学 发展生物学
- 儿科医学 儿科医学
背景情况:
- 先天性冠状动脉异常很少见,大多数病例都是异常左冠状动脉到肺动脉的变体.
- 冠状动脉与大动脉连接的缺失是非常罕见的,通常与其他先天性心脏缺陷一起出现.
研究的目的:
- 报告四个罕见的先天性冠状动脉形缺失大动脉连接的罕见病例.
- 调查这些罕见异常对患者预后和对冠状动脉发育的理解的影响.
主要方法:
- 病例系列描述四名患有独特冠状动脉形的患者.
- 对临床表现,诊断发现和结果的审查.
主要成果:
- 确定了四个不同的冠状动脉-大动脉连接缺失的不同病例.
- 两名患者几乎完全没有心上冠状动脉,其中一人有一个冠状动脉与右肺动脉相连,另一个患有左心室连接.
结论:
- 这些特殊的冠状动脉形带来了不良的预后,并且通常是死后发现的.
- 这些发现,特别是心上冠状动脉完全缺失,需要对人类冠状动脉发育理论进行重新评估.
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