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Updated: Jul 11, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
08:59

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

Published on: December 3, 2020

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评估由Eleveld药理动力学模型捕获的个体间变异性

Sara Hosseinirad1, Klaske van Heusden2, Guy A Dumont3

  • 1Department of Electrical and Computer Engineering, The University of British Columbia, Vancouver, BC, V6T 1Z4, Canada. sarahrad@ece.ubc.ca.

Journal of clinical monitoring and computing
|November 7, 2023
PubMed
概括

与较旧的模型相比,Eleveld的药理动力学模型没有提高麻醉控制的准确性. 这项研究发现,开环或闭环麻醉控制系统的预测性能没有显著差异.

关键词:
闭环控制的闭环控制方法药物动力学 - 药物动力学系统识别 系统识别目标控制输注注射目标控制输注

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