adenosine Tetraphosphate (Ap4 A) 5'RNA

Jiří František Potužník1,2, Ondřej Nešuta1, Anton Škríba1

  • 1Chemical Biology of Nucleic, Acids, Institute of Organic Chemistry and Biochemistry of the CAS, Flemingovo náměstí 2, Prague, 6, Czechia.

概括

研究人员在人类和老鼠细胞中发现了一种新的非正规的RNA盖,即氨酸四酸盐 (Ap4A). 这一发现扩大了我们对RNA化学修饰和转录后基因调节的理解.

相关概念视频

Pre-mRNA Processing: Modification of pre-mRNA Ends01:35

Pre-mRNA Processing: Modification of pre-mRNA Ends

In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a cap to the 5' end of the growing transcript. In this process, a 5' phosphate is replaced by modified guanosine that has a methyl group attached (7-methyl guanosine). This 5' cap helps...
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pre-mRNA Processing02:01

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In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
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Transfer RNA Synthesis02:36

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RNA Editing02:23

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RNA Structure01:19

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RNA Stability01:53

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