在18F-PSMA PET/CT上偶然检测出甲状腺腺瘤
Wouter A M Broos1, Friso M van der Zant2, Remco J J Knol2
1From the Department of Nuclear Medicine, Albert Schweitzer Ziekenhuis, Dordrecht.
Clinical nuclear medicine
|November 7, 2023
概括
使用前列腺特异性膜抗原 (PSMA) 的前列腺癌分期PET/CT偶然发现了一种副甲状腺腺瘤. 这一发现凸显了PSMA PET/CT PET/CT 的重要意义.
科学领域:
- 核医学就是核医学.
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 前列腺特异性膜抗原 (PSMA) 位子发射断层扫描/计算机断层扫描 (PET/CT) 是前列腺癌分期的关键成像方式.
- 瘤成像期间的偶然发现可能会导致诊断出与癌症无关的疾病.
- 初级甲状腺功能障碍是一种常见的内分泌疾病,通常是由甲状腺腺瘤引起的.
研究的目的:
- 报告在PSMA PET/CT期间偶然发现甲状腺腺瘤,用于前列腺癌分期.
- 为了说明PSMA PET/CT在潜在识别非瘤发现方面的有用性.
主要方法:
- 一名患有前列腺癌的70岁男性接受了PSMA PET/CT用于瘤分期.
- 进行了四维CT扫描以进一步描述偶然发现的特征.
- 分析了血清和副甲状腺激素水平.
- 进行了副甲状腺切除术和组织病理学检查.
主要成果:
- PSMA PET/CT显示前列腺吸收率高,与癌症一致,没有淋巴结或远程转移的证据.
- 一个偶然的PSMA-avid结节被确定为右甲状腺叶的背部.
- 结节的特征是,在4DCT上具有快速对比度增强的18毫米质量.
- 血清和副甲状腺激素的升高证实了原发性副甲状腺功能障碍症.
- 组织病理学证实了结节是副甲状腺腺瘤.
结论:
- 在接受前列腺癌成像检查的患者中,PSMA PET/CT可以偶然检测甲状腺腺瘤.
- 这一案例强调了仔细审查图像检测结果的重要性,超出了主要瘤征兆.
- 偶然检测有助于及时诊断和治疗原发性副甲状腺功能障碍.
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