埃塞俄比亚奥罗米亚地区的轨道瘤风险因素
Oumer Shafi Abdurahman1,2, Anna Last1, David Macleod1
1International Centre for Eye Health, Clinical Research Department, Faculty of Infectious and Tropical diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
PLoS neglected tropical diseases
|November 7, 2023
概括
瘤是导致失明的主要原因,与卫生状况不佳和埃塞俄比亚的有关. 改善面部和衣服的洗可以降低儿童的感染风险,强调需要卫生干预措施.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 瘤,由Chlamydia trachomatis (Ct) 引起,是全球导致失明的主要传染病原因.
- 尽管有控制努力,但气管瘤仍然是44个国家的重大公共卫生问题,埃塞俄比亚承担了最高的负担.
- 关于埃塞俄比亚东南部奥罗米亚的传播风险因素和社会经济联系的数据有限.
研究的目的:
- 调查埃塞俄比亚东南部奥罗米亚地区的气管瘤传播风险因素和社会经济地位关联.
- 确定导致儿童和普通人群活跃气管瘤的特定因素.
- 为该地区的向性气管瘤控制干预提供数据.
主要方法:
- 一项涉及沙什梅内农村区247个家庭1211个个体的横截面研究.
- 使用世卫组织指导方针进行活跃气管瘤的临床检查,并通过定量PCR采集结膜拭子以检测CT.
- 通过采访和观察收集有关风险因素的数据,并根据家庭聚类调整多变量分析.
主要成果:
- 活动性气管瘤 (TF1-9) 观察到20.2%的1-9岁儿童;Ct检测到11.3%的这些儿童.
- 多变量分析确定年龄较小,家庭状况最差,脸上有的存在以及眼部泄漏是活性气管瘤的重要风险因素.
- 经常洗脸 (>1/天) 和经常洗衣服 (>=1/周) 与学龄前儿童活跃气管瘤的几率较低有关.
结论:
- 年龄较小,个人卫生状况不佳 (眼睛/鼻子排泄,不经常洗) 和飞眼接触是埃塞俄比亚这一地区瘤的关键风险因素.
- 卫生干预和环境改善对于减少传播和疾病负担至关重要.
- 气管瘤与较低的社会经济地位有关,需要综合控制和减少贫困的战略.
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