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相关概念视频

Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...

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相关实验视频

Updated: Jul 9, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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原创研究:从护士的角度探索药物安全实践.

Laura Arkin1, Andrea A Schuermann, Victoria Loerzel

  • 1Laura Arkin is the director of quality services at the Orlando Health Jewett Orthopedic Institute, Orlando, FL. Daleen Penoyer is the director of the Center for Nursing Research at Orlando Health, Orlando, FL. Andrea A. Schuermann is the manager of quality process improvement and patient safety at Orlando Health South Seminole Hospital, Longwood, FL. Victoria Loerzel is a professor and the Beat M. and Jill L. Kahli Endowed Professor in Oncology Nursing in the College of Nursing at the University of Central Florida, Orlando. The authors receive ongoing support through a research grant from Sigma Theta Tau International Nursing Honor Society, Theta Epsilon chapter. Contact author: Laura Arkin, Laura.Arkin@orlandohealth.com . The authors have disclosed no potential conflicts of interest, financial or otherwise.

The American journal of nursing
|November 7, 2023
PubMed
概括

直接护理护士将环境因素,工作量和系统问题作为药物错误的关键风险. 改善护士培训和让护士参与政策变化对于提高药物安全至关重要.

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相关实验视频

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科学领域:

  • 护理实践 护理实践
  • 患者安全 患者安全
  • 医疗保健系统 医疗保健系统

背景情况:

  • 制备和使用药物是复杂的护理任务.
  • 尽管正在努力减少药物错误,但药物错误仍然很普遍.
  • 直接护理护士的见解对于确定改进机会至关重要.

研究的目的:

  • 探索直接护理护士对药物安全实践的看法.
  • 了解护士对药物错误的经验.

主要方法:

  • 定性描述性研究设计.
  • 在焦点小组和一对一会议上进行的半结构化采访.
  • 使用定性直接内容分析分析的数据.

主要成果:

  • 出现了四个主要主题:护理环境,护士能力,系统影响和错误范式.
  • 混乱的环境,繁重的工作负载和中断增加了药物错误的风险.
  • 护士们对药物错误的定义和范围表示不确定.

结论:

  • 提高药物安全性需要解决环境障碍和加强护士教育.
  • 需要对药物管理和错误定义进行强有力的培训.
  • 修订政策与直接护理护士的投入对于有效的策略至关重要.