分子核性决定性? 两动物的实证证据
Chase H Smith1, Raquel Mejia-Trujillo1, Sophie Breton2
1Department of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Molecular biology and evolution
|November 7, 2023
概括
淡水中的雄性线粒体DNA (mtDNA) 可能抑制雌性发育. 男性mtDNA中的小RNA准女性发育途径,这表明它在性别决定中发挥了作用.
科学领域:
- 进化生物学是进化的生物学.
- 遗传学 是一个遗传学.
- 分子生物学分子生物学
背景情况:
- 核DNA通常决定动物的性别.
- 在一些双动物中,双重单亲遗传 (DUI) 涉及线粒体DNA (mtDNA) 在性别决定中.
- 男性mtDNA (M mtDNA) 的遗传模式类似于Y染色体,这表明它在性别决定中发挥了作用.
研究的目的:
- 研究 mitochondrial 和核 DNA 在淡水 Potamilus streckersoni 的性别决定中的作用.
- 探索线粒体短非编码RNAs (sncRNAs) 在性发育中的功能.
主要方法:
- 使用了DNA,RNA和线粒体sncRNA测序.
- 分析的重点是Potamilus streckersoni,一种淡水鱼物种.
- 研究了基因表达和遗传差异化模式.
主要成果:
- 一个来自M mtDNA的sncRNA被识别出来,准了一条涉及女性发育和线粒的途径.
- 这种sncRNA的目标基因在雌性中显著上调,表明在基因沉默中发挥了作用.
- 没有发现核性决定区域的有力证据,尽管不能排除核因素.
结论:
- 从M mtDNA衍生的sncRNAs可能会抑制这种双鱼物种中的雌性发育.
- 线粒体基因有助于非呼吸功能,包括性别决定.
- 这项研究提供了对双动物不寻常的性别确定系统的见解.
更多相关视频
10:18A Noninvasive Method For In situ Determination of Mating Success in Female American Lobsters Homarus americanus
Published on: February 7, 2014
11.0K
07:53Bioindication Testing of Stream Environment Suitability for Young Freshwater Pearl Mussels Using In Situ Exposure Methods
Published on: September 5, 2018
7.3K
相关概念视频
The Ratio of X Chromosome to Autosomes
8.6K
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
8.6K
Animal Mitochondrial Genetics
7.6K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
7.6K
Meiosis I
40.8K
Meiosis is the division of a diploid cell into haploid cells forming sperm and eggs in animals through differentiation. Meiosis I is the first stage of meiosis, where the genetic recombination of homologous chromosomes and the reduction of the ploidy level by half occurs.
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
40.8K
Meiosis vs. Mitosis
56.7K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
56.7K
Complementation Tests
4.9K
A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
4.9K
Chromosomal Theory of Inheritance
55.4K
In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
55.4K
