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Updated: Jul 11, 2025

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蛋白酶组分PSMD14通过一种组分双基因酶活动驱动骨髓生成

Lin He1, Chunyu Yu2, Sen Qin3

  • 1Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University Health Science Center, Beijing 100191, China; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University International Cancer Institute, Peking University Health Science Center, Beijing 100191, China.

Molecular cell
|November 7, 2023
PubMed
概括

蛋白酶组分PSMD14通过与NSD2相互作用和控制基因表达来调节髓瘤. 抑制PSMD14增强了博特佐米布治疗,并改善了骨髓瘤患者的存活率.

关键词:
19S 调节粒子 19S 调节粒子26S 蛋白质酶体是一种26S蛋白质体.这就是NSD2SD.这是PSMD14在RELA中,您可以使用RELA.博尔特佐米布耐药性 博尔特佐米布耐药性基因组胺甲基化 基因组胺甲基化希斯的无处不在化多发性骨髓瘤是多发性骨髓瘤的一种.t(4;14) 转移转移的地方.

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