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在METTL14-m6A-FOXO3a轴调节自和炎症在结性脊髓炎

Yuting Chen1, Ye Wu1, Lanlan Fang1

  • 1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui 230032, China; The Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, 81 Meishan Road, Hefei, Anhui 230032, China.

Clinical immunology (Orlando, Fla.)
|November 7, 2023
PubMed
概括

甲基转移酶样14 (METTL14) 在结性脊髓炎 (AS) 中降低调节,损害自和增加炎症. 恢复METTL14通过调节叉头盒O3a (FOXO3a) 来缓解AS症状.

关键词:
结性脊柱炎是一种疾病.自自是一种自的过程.这就是FOXO3a.炎症 炎症是一种炎症.在METTL14中,使用的是METTL14m6A 一个很好的.

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