肌态素基因中的多态度与牛的分娩困难和尸体价值之间的关联
Cliona A Ryan1,2, Deirdre C Purfield2, Saeid Naderi3
1Department of Animal Bioscience, Animal and Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Co. Cork, Ireland.
Journal of animal science
|November 7, 2023
概括
肌态素突变会影响牛犊和牛肉的特征. 一些突变增加了分娩难度,但改善了尸体的特征,为牛养殖中的遗传选择提供了潜力.
科学领域:
- 动物遗传学动物遗传学
- 量化遗传学 量化遗传学
- 畜牧养殖 畜牧养殖 畜牧养殖
背景情况:
- 已知myostatin基因突变会影响各种物种的肌肉生长.
- 了解这些突变对牛的经济重要特征的影响,对于养殖计划至关重要.
研究的目的:
- 量化21种已知的肌态素突变与12种牛品种的分娩困难和尸体特征之间的关联.
- 为了确定特定的myostatin变体,可以用于牛的遗传改进.
主要方法:
- 从32,770种母子代组合中对乳腺发症的myostatin基因型的关联分析.
- 混合模型协会分析使用来自129,803只动物的基因型,用于尸体重量,形状和脂肪得分.
- 在混合模型中包括附加的遗传,母体和永久性环境影响.
主要成果:
- 突变基因型nt821,Q204X和F94L与增加的分娩困难显著相关 (P <0.01).
- 大多数myostatin变体与尸体重量,形状和脂肪分数有显著的关联,其中F94L,Q204X和nt821具有最大的影响.
- 突变nt374_51,F94L和E226X改善了尸体的优点,对分娩难度的影响最小.
结论:
- 特定的肌态素突变在分娩容易和尸体质量之间进行了权衡.
- 某些突变,如nt374_51,F94L和E226X,提供了改善的尸体特征和可控的分娩困难的有利组合.
- 考虑到母基因型的myostatin基因型的战略性使用,可以提高尸体的价值,并最大限度地减少牛的分娩问题.
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