探索性腹腔切除术后与马群结肠炎发展相关的危险因素
Stephanie A Givan1, Krista E Estell1, Javier Martinez-Lopez1
1Virginia Tech Marion duPont Scott Equine Medical Center - Internal Medicine, Leesburg, Virginia, USA.
Equine veterinary journal
|November 7, 2023
概括
马的术后结肠炎与更长的住院时间有关,但并没有减少生存率. 关键的危险因素包括骨盆曲肠切,异常的白细胞计数和乳酸水平升高.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 马类手术 马类手术
- 胃肠病学 胃肠病学
背景情况:
- 大肠炎的诊断显著影响住院马的发病率和死亡率.
- 探索性腹腔切除术后感染性结肠炎的发生率仍未得到充分研究.
研究的目的:
- 为了确定与大肠炎后探索性腹腔切除术发展相关的危险因素.
- 为了研究马匹探索性腹腔切除术后感染性结肠炎的危险因素.
主要方法:
- 追溯病例控制研究分析了2011-2020年504匹马的医疗记录.
- 后勤回归和双变量分析评估了风险因素和结肠炎之间的关联.
- 主要结局:诊断大肠炎后探索性腹腔切除术.
主要成果:
- 8.3%的马 (42/504) 患有术后结肠炎.
- 大肠炎的重要危险因素包括骨盆曲肠切除术 (OR=3.7),术后白血症/白血细胞症 (OR=21.2),以及血乳酸2.0-4.0 mmol/L (OR=3.0).
- 大肠炎患者住院时间较长 (9 vs. 7 天),但存活率与出院率相似 (95% vs. 93%).
结论:
- 马的术后结肠炎与住院时间的增加有关,但生存率没有降低.
- 骨盆曲肠切除术,白细胞数量变化和血乳酸水平升高是显著的危险因素.
- 由于检测方案的变化和病例数量较少,无法确定感染性结肠炎的危险因素.
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