瓦尔·德希布朗风险评分II 对于心肌梗塞和心脏死亡
Guillermo Romero-Farina1,2,3,4,5, Santiago Aguadé-Bruix6,2,3, Ignacio Ferreira González5,7
1Nuclear Cardiology, Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain guiromfar@gmail.com.
Open heart
|November 7, 2023
概括
一个新的Vall d'Hebron风险评分II (VH-RS-II) 有效地分层了心肌梗塞 (MI) 和心脏病死亡 (CD) 的风险. 这一分数使用封闭的SPECT变量,用于有或没有先前心脏病发作或冠状动脉再血管化的患者.
科学领域:
- 心脏病学 心脏病学
- 核心脏病学 核心脏病学
- 医疗成像医学成像
背景情况:
- 对心脏事件的准确风险分层在心血管医学中至关重要.
- 现有的风险评分可能无法完全捕捉患有或没有先前心肌梗塞 (MI) 或冠状动脉再血管 (CR) 的患者的风险.
- 门式单光子发射CT (SPECT) 为风险评估提供了有价值的功能和解剖信息.
研究的目的:
- 开发和验证一种新的风险评分,即Vall d'Hebron风险评分-II (VH-RS-II).
- 预测在接受封闭式SPECT的患者中发生非致命心肌梗塞 (MI) 和/或心脏死亡 (CD) 的风险.
- 在随访期间接受冠状动脉再血管化 (CR) 的患者从分析中排除.
主要方法:
- 对5215名连续接受封闭式SPECT的患者进行分析.
- 分为两组:没有先前的MI和/或CR (2960名患者) 和先前的MI和/或CR (2255名患者).
- 多变量考克斯和逻辑回归分析以确定心脏事件 (CE) 的独立预测因素,随后在679名患者中进行验证.
主要成果:
- 在没有先前的MI / CR的患者中,CE的预测因素包括年龄,糖尿病,代谢等价物 (MET),ST段抑郁,射出分数 (EF) 和总压力评分 (C统计:0.8).
- 在先前患有MI/CR的患者中,CE的预测因素包括年龄,男性性别,吸烟状态,MET,ST段抑郁,EF和总分差分数 (C统计:0.8).
- 在这两组患者中,VH-RS-II表现出良好的预测准确性.
结论:
- 从临床实践和封闭的SPECT变量中获得的VH-RS-II,可以有效地分层MI和CD的风险.
- 该得分适用于有或没有心脏病发作或心脏病复发史的患者.
- 在心脏病学中,VH-RS-II为个性化风险评估提供了有价值的工具.
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