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免疫瘤微环境在乳头脏细胞癌中的综合分析

Manon de Vries-Brilland1, Nathalie Rioux-Leclercq2, Maxime Meylan3

  • 1Department of Medical Oncology, Integrated Centers of Oncology (ICO) Paul Papin, Angers, France.

Journal for immunotherapy of cancer
|November 7, 2023
PubMed
概括

乳头性细胞癌 (pRCC) 的免疫微环境尚不清楚. 这项研究确定了一种"免疫丰富"的亚型,与转移性PRCC的更糟糕的预后和潜在的免疫疗法反应有关.

关键词:
基因表达简介 基因表达简介免疫治疗是一种免疫疗法.细胞癌是细胞癌.瘤生物标志物 瘤生物标志物瘤微环境 瘤微环境

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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