大麻和副产品对人体测量措施的影响:系统审查和元分析
Marcela Gomes Reis1,2, Andrea J F Ferreira2,3, Mohammad Hassan Sohouli4
1Faculdade Ciências Médicas de Minas Gerais, Belo Horizonte, Brazil.
International journal of obesity (2005)
|November 7, 2023
概括
大麻使用可以通过减少体重和腰围来帮助治疗肥胖. 需要进一步的研究来证实这些对人体质量指数和身体脂肪的影响.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 肥胖是一个主要的公共卫生问题.
- 以前关于大麻和健康的研究已经产生了不一致的结果.
- 关于大麻对肥胖的影响缺乏共识.
研究的目的:
- 评估大麻及其副产品对人类测量的影响.
- 综合了关于大麻使用和身体测量的随机对照试验的证据.
主要方法:
- 在2023年3月之前,对多个数据库 (MEDLINE,Embase,Cochrane图书馆,Web of Science) 进行系统搜索.
- 包括随机对照试验,评估大麻/副产品使用以及体重,体重指数 (BMI) 和腰围 (WC) 的变化.
- 使用R软件 (4.2.1版本) 进行的元分析.
主要成果:
- 大麻使用与体重 (-1.87公斤) 和腰围 (-2.19厘米) 的减少有关.
- 在子组分析中,更长的随访期与更大的BMI下降相关.
- 大麻素CB1受体激活显示身体脂肪增加 (1.70).
结论:
- 大麻及其副产品可以作为肥胖管理的辅助剂.
- 这些物质显示出降低与肥胖相关的关键人体测量指标的潜力.
- 需要对特定的大麻素效应进行进一步的研究.
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