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快速降低对毒素的敏感性:土耳其的一项描述性研究

Selma Yeşilkaya¹, Kurtuluş Aksu¹, Gürgün Tuğçe Vural Solak¹

¹Division of Immunology and Allergy, University of Health Sciences, Ankara Atatürk Sanatory Education and Research Hospital, Ankara, Turkey.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

|November 8, 2023

概括

快速药物脱敏 (RDD) 能够有效地控制非小细胞肺癌 (NSCLC) 患者的高敏感性. 这种可靠的程序允许成功完成对过敏个体的必要的纳税治疗.

科学领域:

在瘤学瘤学.
药理学药理学是指药理学的学科.
临床医学临床医学

背景情况:

药物过敏反应 (DHRs) 在癌症治疗中构成了挑战.
塔克桑是非小细胞肺癌 (NSCLC) 的关键化疗药物.
管理DHR对于治疗坚持和患者的结果至关重要.

研究的目的:

在接受纳税剂的NSCLC患者中描述DHR.
评估快速药物脱敏 (RDD) 对于高素过敏的疗效和安全性.
评估尽管DHRs,但完成taxane化疗的可行性.

主要方法:

在45名高高灵敏的NSCLC患者进行了回顾性横截面研究.
标准的3袋,12步RDD协议给所有患者.
通过完成循环而没有立即或延迟反应来定义RDD的成功.

主要成果:

高成功率:45名患者中有43名 (95.6%) 完成了RDD的纳税循环.
总体而言,RDD周期的成功率为98.9% (183个周期中的181个).
只有2名患者 (4.4%) 经历了RDD失败.

结论:

快速药物脱敏是一种可靠且有效的程序,用于对高素过敏的患者.
通过RDD,可以进行并完成一线的分类剂化疗.
这种方法改善了患有DHRs的NSCLC患者的治疗选择.

关键词:

纳税人就是纳税人.突破性的过敏反应突破性的过敏反应药物过敏反应药物过敏反应非小细胞肺癌的肺癌.快速降低药物敏感性的方法

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