来自COVID-19肺炎重症患者的临床和时间放射学发现:一项描述性研究
Ye Tian1, Yuqiong Wang1,2, Min Liu3
1National Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
计算机断层扫描 (CT) 扫描显示,随着时间的推移,危急的COVID-19肺炎患者的肺部变化正在演变,从最初的地面玻璃不透明度发展到巩固和后来的网膜化. 葡萄糖皮质类药物可能有助于管理间歇性变化.
科学领域:
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 由SARS-CoV-2引起的COVID-19大流行病在2019年底出现.
- 关键的COVID-19肺炎的放射性变化需要随着时间的推移进一步表征.
研究的目的:
- 描述不同疾病阶段的危急COVID-19肺炎患者的计算机断层扫描 (CT) 发现.
- 分析肺部异常的时间演变.
主要方法:
- 评估了11名危急COVID-19患者的临床和实验室特征.
- 根据症状发作 (在2周内,2-4周内,4-6周内和>6周内) 分类CT扫描成四组.
- 分析和比较成像特征,包括CT总得分和肺部段参与.
主要成果:
- 病变主要是双边的 (92.5%).
- 地面玻璃的不透明度 (GGO) 很早就很常见,在后来的阶段演变为巩固和网络化.
- 在晚期疾病阶段观察到纤维化表现.
结论:
- 危急的COVID-19肺炎会出现暂时变化的CT特征,从单边进展到扩散双边GGO和巩固,最终导致网膜化.
- 低剂量葡萄糖皮质类药物可能对CT扫描显示的间歇性变化患者有益.
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