预测的身体组成变化与心力衰竭发生之间的关联:全国人口研究
Ho Geol Woo1, Dong-Hyeok Kim2, Hyungwoo Lee3
1Department of Neurology, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
Frontiers in endocrinology
|November 8, 2023
概括
骨肌肉质量的减少预测了男性和女性心力衰竭 (HF) 的风险. 身体脂肪质量的变化也与HF有关,但这种关联在女性中似乎具有悖论性.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 身体组成分析 身体成分分析
背景情况:
- 心力衰竭 (HF) 是一个重要的公共卫生问题.
- 对身体组成变化和HF发病率的大规模研究是有限的.
- 了解这些关联对于预防策略至关重要.
研究的目的:
- 调查身体组成的变化与心力衰竭 (HF) 的发生之间的关系.
- 分析与预测的身体脂肪质量指数 (pBFMI),预测的尾骨肌肉质量指数 (pASMI) 和预测的瘦体质量指数 (pLBMI) 的关联.
主要方法:
- 利用了接受国家健康检查的2,036,940名个人 (2010-2013) 的数据.
- 使用验证的人类测量预测方程,评估身体组成的变化.
- 根据在中位数7.59年的随访期间至少有两个或更多的索赔,定义了HF发生率.
主要成果:
- 降低的pASMI和pLBMI与男性和女性中HF发生率的增加有关.
- 增加的pBFMI与男性中较高的HF发生率有关.
- 在女性pBFMI变化和HF发生之间观察到一个矛盾的关联.
结论:
- 骨肌肉量减少是心力衰竭的重要危险因素.
- 身体脂肪质量的变化对心力衰竭风险的影响在性别之间有所不同.
- 在评估身体组成和HF风险时,性别特定的考虑是至关重要的.
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