糖尿病和胆结石之间的关联:全国性基于人口的队列研究
Rani Ratheesh1, Michael T Ulrich2,3, Sherief Ghozy4,5
1Department of Gastroenterology, Aster Al Raffah Hospital, Muscat, Oman.
Przeglad gastroenterologiczny
|November 8, 2023
概括
糖尿病 (DM) 显著增加患上胆结石 (胆结石) 的风险. 胰岛素治疗也是成年人胆结石形成的显著预测因素.
科学领域:
- 内分泌学 在内分泌学.
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 关于糖尿病 (DM) 和胆病之间的关联存在不一致的证据.
- 了解这种联系对于公共卫生和临床管理至关重要.
研究的目的:
- 为了研究糖尿病和胆结石之间的关联.
- 在全国人口基队列中识别常见的相关风险因素.
主要方法:
- 利用了来自国家健康和营养检查调查 (NHANES) 数据库 (2017-2018) 的数据.
- 分析了来自5376名成年参与者的数据.
- 使用未调整和调整后勤回归模型.
主要成果:
- 在糖尿病和胆结石发生率增加之间发现了显著的关联 (OR = 1.52;95% CI: 1.20-1.92).
- 胰岛素使用是胆病的显著预测因素 (OR = 1.52;95% CI: 1.05-2.19).
- 糖尿病的持续时间没有显著影响胆结石率.
结论:
- 糖尿病和胰岛素治疗被确定为胆病的潜在风险因素.
- 进一步的研究可能会阐明这种关联背后的确切机制.
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