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生殖器疹症状史是否预测了简单疹病毒2型抗体的阳性?
Jessica Perez1, Katherine A Lewis1, Silver Vargas2
1Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
International journal of STD & AIDS
|November 8, 2023
概括
基于症状的简单疹病毒-2 (HSV-2) 查是不可靠的. 许多无症状的个体对HSV-2的测试结果呈阳性,表明需要更好的诊断工具.
科学领域:
- 传染性疾病 传染性疾病
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 由简单疹病毒-2 (HSV-2) 引起的生殖器病导致显著的发病率.
- 目前的HSV-2查依赖于症状史,但没有有效的工具存在.
研究的目的:
- 评估症状史在查HSV-2感染中的有用性.
- 评估参加性传播疾病诊所的无症状成年人HSV-2患病率.
主要方法:
- 在秘鲁利马的性病诊所,无症状的成年人完成了症状调查,并接受了HSV-2血清检测.
- 使用西方斑点测试证实了不确定的结果.
- 分析了症状与HSV-2阳性之间的关联.
主要成果:
- 总体HSV-2抗体患病率,包括确认测试,为59.5%.
- 在没有先前症状的参与者中,很大一部分 (31.2%) 呈HSV-2阳性.
- 在症状史和HSV-2抗体阳性之间没有发现显著的关联.
结论:
- 目前基于症状史的HSV-2查建议可能无效.
- 开发更准确的症状查工具或改进的HSV-2抗体测试是必要的.
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