预后营养指数和死亡率在患有心室关节通道感染的患者中
Sebnem Nergiz1, Pinar Aydin Ozturk1,2
1Department of Nutrition and Dietetics, Ataturk Faculty of Health Sciences, Dicle University, Diyarbakir, Turkey.
Clinical pediatrics
|November 8, 2023
概括
低预后营养指数 (PNI) 与患有腹腔关节 (VPS) 感染的儿科患者的死亡率较高有关. 这项研究强调PNI是这些关键病例中结果的潜在预测因素.
科学领域:
- 儿科医学 儿科医学
- 传染性疾病 传染性疾病
- 神经外科 神经外科
背景情况:
- 腹腔关突变 (VPS) 放置在儿科水头管理中很常见.
- 感染VPS是一种严重的并发症,增加了发病率和死亡率.
- 预后因素的早期识别对于管理儿科VPS感染至关重要.
研究的目的:
- 调查诊断VPS感染的儿科患者的预后营养指数 (PNI) 和死亡率之间的关联.
- 确定与该患者队列的生存相关的临床和实验室参数.
主要方法:
- 对63名儿科患者的回顾性分析证实VPS感染和阳性脑脊液 (CSF) 培养.
- 幸存者和非幸存者组之间的实验室发现 (CSF和血液参数) 的比较.
- 预后营养指数 (PNI) 的计算和评估.
主要成果:
- 非幸存者患者的CSF白细胞,CSF葡萄糖,CSF蛋白质,CSF/血糖比,淋巴细胞计数,血清白蛋白和PNI水平显著降低.
- 相反,没有幸存的患者血糖和C反应蛋白 (CRP) 的水平较高.
- 较低的PNI被确定为与死亡风险增加相关的重要指标.
结论:
- 预后营养指数 (PNI) 可能成为患有VPS感染的儿科患者死亡率的有价值的预测标志物.
- 正如PNI所反映的营养状况,在VPS感染的临床结果中发挥着作用.
- 需要进一步的研究来探索营养支持在管理VPS感染中的治疗影响.
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