在怀孕和产后抑郁症状期间补充叶酸
Bárbara Heather Lutz1, Iná da Silva Dos Santos1, Marlos Rodrigues Domingues1,2
1Universidade Federal de Pelotas . Departamento de Medicina Social . Programa de Pós-Graduação em Epidemiologia . Pelotas , RS , Brasil.
Revista de saude publica
|November 8, 2023
概括
在怀孕期间补充叶酸并没有显示与产后三个月母亲抑郁症状的关联. 这项研究发现,产前叶酸摄入量与产后抑郁症的发生之间没有联系.
科学领域:
- 产科和妇科 产科和妇科
- 围产期心理健康 围产期心理健康
- 营养精神病学 营养精神病学
背景情况:
- 在产前期,母亲的心理健康至关重要.
- 产后抑郁症影响了大量女性.
- 叶酸在神经系统的发育和功能中起着至关重要的作用.
研究的目的:
- 调查怀孕期间叶酸补充剂与母亲抑郁症状之间的关联.
- 为了评估产后三个月的抑郁症状,与叶酸摄入水平相关.
主要方法:
- 分析了4046名女性的队列.
- 参与者根据叶酸补充剂的持续时间 (没有,一个季度,两个-三个季度) 进行分组.
- 抑郁症状是使用爱丁堡产后抑郁量表 (EPDS) 测量产后三个月.
主要成果:
- 轻度抑郁症状 (EPDS ≥10) 的患病率在非使用者中为26.8%,在使用叶酸者中为18.1%.
- 15.7%的非使用者和9.1-9.4%的使用者报告了中度至严重的抑郁症状 (EPDS≥13).
- 经过调整后的分析显示,叶酸使用与产后抑郁症状之间没有统计学上显著的关联.
结论:
- 产前叶酸补充与三个月后产后抑郁症的风险降低无关.
- 这些发现表明,怀孕期间的叶酸摄入量不会影响患产后抑郁症状的可能性.
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