一项系统性审查,调查出生体重是否会影响成年人的自主神经系统
Giovanna de Paula Vidigal1, Luana Almeida Gonzaga1, Andrey Alves Porto1
1Universidade Estadual Paulista, Presidente Prudente, SP, Brazil.
概括
出生时体重超出正常范围,可能会对成人自主神经系统产生负面影响,可能导致心血管疾病. 早期和持续的健康监测对于预防至关重要.
科学领域:
- 心血管健康 心血管健康
- 自主神经系统功能 自主神经系统功能
- 健康和疾病的发育起源 (DOHaD)
背景情况:
- 自主神经系统 (ANS) 调节非自愿的身体功能,其发展可以受到早期生活因素的影响.
- 出生体重是胎儿生长和发育的关键指标,可能会将产前情况与成人健康结果联系起来.
研究的目的:
- 系统地审查有关出生体重与成人自主神经系统功能之间的关联的现有文献.
- 确定异常出生体重对晚年心血管健康的潜在影响.
主要方法:
- 在多个数据库 (MEDLINE,CINAHL,Web of Science,Scopus,Cochrane Library) 中对出版物的全面系统审查,没有年份或语言限制.
- 搜索策略集中在与自主神经系统,心率,心率变化和出生体重相关的术语上.
- 纳入标准侧重于在成人群体中检查ANS和出生体重的研究,结果分析了9篇出版物.
主要成果:
- 对9项研究 (两个队列,七项横截面) 的分析表明,极端,非常低,低或高的出生体重可能会影响成人自主神经系统.
- 有证据表明,出生时正常体重的偏差与成年后改变的ANS功能之间存在联系.
结论:
- 出生的体重超出正常范围可能会对成人自主神经系统产生负面影响,导致自主功能障碍.
- 这种功能障碍会增加成年人患心血管疾病的风险.
- 强调需要从怀孕到成年期进行持续的健康监测,以实施预防性护理战略.
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