基于动脉脊柱标记的脑血管疾病MR血管学:原理和临床应用
Osamu Togao1, Makoto Obara2, Koji Yamashita3
1Department of Molecular Imaging & Diagnosis, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Journal of magnetic resonance imaging : JMRI
|November 8, 2023
概括
动脉旋转标记 (ASL) 磁共振血管造影 (MRA) 为对比度增强成像提供了一个非侵入性的替代方案. 本综述详细介绍了各种ASL-MRA技术,强调了它们的原理和用于脑成像的临床应用.
科学领域:
- 放射学 放射学是一门学科.
- 医疗成像医学成像
- 神经成像是一种神经成像.
背景情况:
- 动脉旋转标记 (ASL) 是一种非侵入性技术,使用动脉血液作为脑 perfusion 成像的内源性追踪器.
- 基于ASL的内磁共振血管造影 (MRA) 与计算机断层扫描 (CT) 血管造影和传统的MRA技术相比具有优势.
- 它避免了对比剂,并克服了飞行时间 (TOF) MRA的限制.
研究的目的:
- 审查各种基于ASL的MRA技术的原则,临床应用和特征.
- 突出ASL-MRA的进步,包括脉冲,伪连续,速度选择和加速选择方法.
- 讨论新的ASL-MRA方法,如无声MRA和选择性4DASL MRA.
主要方法:
- 对基于ASL的MRA技术现有文献的审查.
- 讨论不同的ASL标签方案 (脉冲,伪连续,速度选择性,加速选择性).
- 检查先进的MRA方法 (无声MRA,超短回声时间MRA,选择性4D ASL MRA).
主要成果:
- ASL-MRA提供无对比剂的脑内血管成像.
- 与脉冲ASL相比,伪连续ASL提供了更好的信号噪声比率 (SNR).
- 专业技术解决了特定的挑战,例如金属文物 (静音MRA) 和提供DSA类成像 (容器选择性4D ASL MRA).
结论:
- 基于ASL的MRA是一种通用且不断发展的非侵入性神经成像模式.
- 不同的ASL-MRA技术为临床应用提供了明显的优势.
- 持续的发展有望进一步提高对脑血管疾病的诊断能力.
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