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Updated: Jun 30, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
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Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

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在扩散性创伤性脑损伤后,皮层神经元平衡和认知功能受损取决于微质和I型干扰素反应

Jonathan M Packer1,2, Chelsea E Bray3, Nicolas B Beckman2

  • 1Department of Neuroscience, The Ohio State University, Columbus, Ohio, USA.

Glia
|November 8, 2023
PubMed
概括

创伤性脑损伤 (TBI) 损害神经元的稳态,增加1型干扰素 (IFN-I) 反应,导致认知缺陷. 针对STING依赖的IFN-I信号,使用STING绝杀或氨酸扭转了这些损害.

关键词:
这是一个TBI,TBI.认知功能障碍 认知功能障碍这是一种炎症炎症炎症炎症.干扰子I型干扰子 I型干扰子微质细胞中的微质细胞干扰素基因的刺激剂.

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