尿素周期障碍在严重病情严重的成年人中
Micah T Long1, Jacqueline M Kruser2, Shane C Quinonez3
1Departments of Anesthesiology & Internal Medicine, University of Wisconsin Hospitals and Clinics.
Current opinion in clinical nutrition and metabolic care
|November 8, 2023
概括
尿素循环障碍 (UCD) 可以导致严重的氨升高和神经损伤. 早期查和综合管理对于预防新生儿和成人的不可逆转伤害至关重要.
科学领域:
- 生物化学 生物化学
- 神经学 神经学
- 遗传学 是一个遗传学.
背景情况:
- 尿素循环障碍 (UCDs) 破坏氨的新陈代谢,导致高氨血.
- 严重的超血导致不可逆转的神经损伤,经常在新生儿中诊断出来.
- 轻微的UCD可以在生理压力期间在成年期出现,需要更广泛的查.
结论:
- 了解UCD对于临床医生来说至关重要,以防止严重的神经损伤或死亡.
- 及时诊断和管理UCD可以防止患者的病情恶化.
- 聚焦治疗与支持性重症监护相结合,改善了UCD患者的治疗结果.
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