产前维生素B12状态和4岁儿童的认知功能:ECLIPSES研究
Josué Cruz-Rodríguez1, Josefa Canals-Sans1,2,3, Carmen Hernández-Martínez1,2,3
1Nutrition and Mental Health Research Group (NUTRISAM), Universitat Rovira i Virgili (URV), Tarragona, Spain.
Maternal & child nutrition
|November 8, 2023
概括
怀孕早期母亲的维生素B12水平与4岁儿童更好的工作记忆有关. 在怀孕第一季度获得足够的维生素B12有助于认知发育,影响学龄前儿童的工作记忆表现.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 发展心理学 发展心理学
背景情况:
- 母亲的维生素B12缺乏与儿童的认知缺陷有关.
- 母亲的维生素B12与学龄前儿童的认知功能之间的关联仍未得到充分探索.
研究的目的:
- 研究怀孕期间母亲的维生素B12水平与4岁儿童的认知功能之间的关系.
- 为了确定第一和第三个三个月的维生素B12水平是否对孩子的认知有不同的影响.
主要方法:
- 在西班牙 (2013-2017年) 的249对母婴对进行了纵向前性研究.
- 测量母亲的维生素B12水平在第一和第三个三个月.
- 在4岁时使用韦克斯勒学前和初级智力表 (WPPSI-IV) 和NEPSY-II.II) 评估儿童的认知功能.
主要成果:
- 在第一季度母亲的维生素B12和儿童的工作记忆指数之间发现了显著的关联.
- 怀孕早期母亲维生素B12水平较高 (第二和第三胎) 的孩子在工作记忆指数上得分明显更高.
- 在第三个月的维生素B12水平和儿童的工作记忆之间没有发现显著的关联.
结论:
- 在怀孕初期保持足够的母体维生素B12对于学龄前儿童的最佳工作记忆发展至关重要.
- 对于这种特定的认知结果,第一季度的维生素B12状态似乎比第三季度的状态更为关键.
- 这些发现强调了产前营养对儿童长期认知结果的重要性.
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