野生虫肠道微生物群中宿主饮食协会和族系的显著影响
Mariah E Donohue1, Amanda K Rowe2, Eric Kowalewski3
1Department of Biology, University of Kentucky, Lexington, KY, USA. Mariah.Donohue@uky.edu.
ISME communications
|November 8, 2023
概括
的肠道微生物组 (GMs) 主要是由宿主进化形成的,表现出强烈的生物共生. 饮食也影响了转基因多样性,特别是在较古老的微生物系中,这表明早期的共同进化.
科学领域:
- 微生物生态学 微生物生态学
- 进化生物学是进化的生物学.
- 灵长类生物学的灵长类生物.
背景情况:
- 哺乳动物肠道微生物组 (GMs) 对宿主健康和生态相互作用至关重要.
- 影响转基因变异的因素包括宿主基因,饮食和息地.
- 在一些哺乳动物中观察到的类交生,即相关物种共享类似的转基因,在一些哺乳动物中观察到的.
研究的目的:
- 为了研究野生的生物共生.
- 确定的肠道微生物群多样性与饮食协会和息地等特征之间的相关性.
- 了解灵长类动物肠道微生物组合的进化驱动因素.
主要方法:
- 从15种野生毛动物的便样本中测序了16S rRNA基因.
- 遗传学回归分析,以评估宿主遗传学对转基因生物的影响.
- 使用UniFrac,Bray-Curtis和Jaccard指标进行肠道微生物群多样性的比较.
主要成果:
- 在虫肠道微生物组中有强有力的生物共生证据.
- 饮食协会和肠道微生物群多样性之间的显著相关性 (UniFrac指标).
- 多样性指标的差异表明,饮食与较老的微生物群更强烈相关.
结论:
- 的肠道微生物群多样性主要是由宿主基因形成的.
- 对肠道微生物群的饮食影响似乎早于大的进化辐射.
- 微生物共生体在的适应和多样化中发挥着重要作用.
更多相关视频
08:14A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
Published on: February 28, 2018
8.9K
05:28Analysis of Fecal Microbiota Dynamics in Lupus-Prone Mice Using a Simple, Cost-Effective DNA Isolation Method
Published on: May 2, 2022
2.2K
相关概念视频
Anatomy of the Intestines
72.1K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.1K
What is Monogastric Digestion?
71.3K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.3K
Applications of Molecular Taxonomy
24
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
24
