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无细胞生物合成与深度学习相结合,加速了抗微生物的新开发

Amir Pandi1, David Adam2,3, Amir Zare2

  • 1Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany. amir.pandi@mpi-marburg.mpg.de.

Nature communications
|November 8, 2023
PubMed
概括

研究人员开发了一种快速,低成本的无细胞蛋白质合成 (CFPS) 管道,以发现新型抗菌 (AMPs). 这种方法与深度学习相结合,确定了有效的AMP,对抗耐药细菌有效,而不会诱导耐药性.

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