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预后关联支持按身体表面积的回声心脏学指数化大小测量
Angus S Y Fung1,2, Dhnanjay Soundappan1,2, Daniel E Loewenstein3
1Kolling Institute, Royal North Shore Hospital, and University of Sydney, Kolling Building, Level 12, St Leonards, Sydney, NSW, 2065, Australia.
Scientific reports
|November 8, 2023
概括
身体表面积 (BSA) 有效地对所有身体质量指数 (BMI) 类别的生存预测进行心声回声测量指数. 替代体型指标在预后性能方面没有比BSA提供临床上显著的改善.
科学领域:
- 心脏病学 心脏病学
- 生物统计学 生物统计学
- 医疗成像医学成像
背景情况:
- 身体表面积 (BSA) 是指数化心声回声测量的标准.
- 它在体重不足或肥胖患者 (BMI <18.5或≥30 kg/m2分别) 的实用性仍在争论中.
- 对心声回声测量的最佳体型索引仍然是一个研究领域.
研究的目的:
- 为了确定一个最佳的身体尺寸索引度指标,用于心声回声测量.
- 为了确定是否存在比BSA优越的指标来预测各种BMI类别的生存率.
- 评估各种体型索引方法的预后性能.
主要方法:
- 对来自澳大利亚国家心声数据库的成年患者进行了生存分析.
- 心声测量 (例如,左心室直径和质量) 被分析为不同体型指标的未索引和索引.
- 五年心血管死亡率作为评估预后表现的主要终点.
主要成果:
- 在所有BMI组 (体重不足,正常/超重,肥胖) 中,BSA的索引显示出与未索引的指标相比,更好的预后表现.
- BSA索引产生更高的C-统计数据,表明更好的生存预测准确性.
- 替代体型指标 (瘦身量,身高,体重变化) 没有比BSA.提供临床上有意义的改善.
结论:
- 通过BSA对心声回声测量进行索引,可以提高预后性能,无论患者的BMI如何.
- 在心声回声学中,BSA仍然是体型索引的强大和有效的指标.
- 没有其他身体尺寸指标为生存预测提供了比BSA在临床上显著的优势.
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