在罕见和难以治愈的疾病中用于药物重新定位的新的in silico支架跳跃方法

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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Published on: December 11, 2016

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Mao Tanabe1, Ryuichi Sakate1, Jun Nakabayashi2

  • 1Laboratory of Rare Disease Information and Resource Library, Center for Intractable Diseases and ImmunoGenomics Research, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Osaka, Japan.

Scientific reports
|November 8, 2023
PubMed
概括

这项研究介绍了AI-AAM,这是一种用于罕见疾病中药物重新定位 (DR) 的新型虚拟查方法. 该技术成功地通过保持药理活性并建议改进的替代品来识别潜在的新药候选者.

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