揭示了两动物和爬行动物病毒的未被描述的多样性
Emma F Harding1, Alice G Russo1,2, Grace J H Yan1
1School of Biotechnology and Biomolecular Sciences, UNSW Sydney, Kensington, NSW, Australia.
ISME communications
|November 8, 2023
概括
研究人员在两动物和爬行动物中发现了26种新病毒和8种已知的病毒,扩大了已知的病毒组. 这项研究有助于了解和保护脆弱的爬行动物和两动物种群.
科学领域:
- 病毒学 病毒学
- 类学 类学 类学
- 基因组学就是基因组学.
背景情况:
- 两动物和爬行动物是重要的脊椎动物群体,但它们的病毒多样性仍然在很大程度上未被探索.
- 这些外热脊椎动物通常居住在特定的环境中,使它们易受病毒爆发和人口减少的影响.
研究的目的:
- 在两动物和爬行动物中识别新的和已知的病毒,使用metatranscriptomic数据.
- 扩大对全球两动物和爬行动物病毒组的理解,并确定对这些种群的潜在威胁.
主要方法:
- 选了来自25个国家的122个物种的235个RNA测序数据集.
- 分析了RNA和DNA病毒转录,包括在转录学研究中经常被忽视的转录.
主要成果:
- 鉴定了26种新型病毒和8种先前表征的病毒,来自15个病毒家族.
- 发现了10种DNA病毒 (Papillomaviridae,Parvoviridae,Circoviridae,Adomaviridae) 和25种RNA病毒 (包括Arteriviridae,Tobaniviridae,Hantaviridae,Rhabdoviridae). 发现了10种DNA病毒 (包括Papillomaviridae,Parvoviridae,Circoviridae,Adomaviridae) 和25种RNA病毒 (包括Arteriviridae,Tobaniviridae,Hantaviridae,Rhabdoviridae).
- 在RNA病毒中发现了家族间重组的证据,并确定了Adomaviridae家族的新成员.
结论:
- 这项研究显著扩大了两动物和爬行动物的已知病毒组.
- 识别了可能致病的病毒,可能会影响人口健康和保护工作.
- 提供对病毒基因组复杂性和重组的见解,为未来的管理和治疗策略提供信息.
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