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Updated: Jul 11, 2025

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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Published on: March 24, 2015

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具有替代NF-κB通路缺陷的人类I型IFN的自身抗体

Tom Le Voyer1,2, Audrey V Parent3, Xian Liu3

  • 1Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Paris, France. tom.le-voyer@institutimagine.org.

Nature
|November 8, 2023
PubMed
概括

在NIK,RELB或NF-κB2的遗传缺陷导致对I型干扰素 (IFN) 的自身抗体,增加严重的COVID-19风险. 这会影响胸膜AIRE细胞的发育,与APS-1不同.

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