系统性免疫炎症指数 (SII) 对中风相关肺炎的预测值
Zhanhang Cui1, Sai Kuang1, Xiaorong Yang2
1School of Public Health, Kunming Medical University, Kunming, Yunnan Province, China.
Brain and behavior
|November 8, 2023
概括
系统性免疫炎症 (SII) 指数是急性中风患者中风相关肺炎 (SAP) 的重要预测指标. 较高的SII水平表明开发SAP的风险增加,有助于早期检测.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 肺部病理学 肺部病理学
背景情况:
- 与中风相关的肺炎 (SAP) 是急性中风的常见并发症.
- 早期识别SAP高风险患者对于及时干预至关重要.
- 系统性免疫炎症 (SII) 指数是一种反映系统性炎症的潜在生物标志物.
研究的目的:
- 评估SII指数对急性中风患者SAP发生的预测能力.
- 确定SII是否是SAP开发的独立风险因素.
主要方法:
- 对395名急性中风患者的回顾性分析,这些患者在中风发作后24小时内入院.
- 收集人口统计数据,中风特征,临床分数 (NIHSS,GCS) 和实验室测试,包括SII.
- 后勤回归和ROC曲线分析,以评估SII对SAP的预测价值.
主要成果:
- 113名患者 (28.6%) 患有SAP;他们的SII水平明显高于非SAP组 (p < .05).
- 较高的SII是SAP的一个独立风险因素 (HR=1.081每100个单位,p < .001).
- 在预测SAP时,ROC分析显示SII的AUC为0.752,灵敏度为61.9%,特异性为76.2%,截止值为861.01.
结论:
- SII指数是急性中风患者SAP的独立风险因素.
- SII指数显示了SAP开发的预测价值,有助于风险分层.
更多相关视频
相关概念视频
Psychoneuroimmunology: Cardiovascular Disease
33
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
33
Pneumonia III: Complications and Assessment
241
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
241


