由于使用隐形眼镜,眼皮表面感觉神经的功能变化在年轻的症状和无症状使用者中发生
José Ángel Pastor-Zaplana1,2, Juana Gallar1,3, M Carmen Acosta1
1Instituto de Neurociencias, Universidad Miguel Hernández-CSIC, Sant Joan d'Alacant, Spain.
Investigative ophthalmology & visual science
|November 8, 2023
概括
隐形眼镜的佩戴会改变角膜神经功能和膜稳定性,即使在无症状的用户中也是如此. 有症状的佩戴者表现出降低的感冒敏感性,表明潜在的神经损伤和炎症.
科学领域:
- 眼科医生 眼科 眼科
- 神经科学是一个神经科学.
- 角膜生理学 角膜生理学
背景情况:
- 隐形眼镜 (CL) 磨损是常见的,但可能导致眼睛表面并发症.
- 了解角膜敏感性的亚临床变化对于早期发现CL引起的问题至关重要.
研究的目的:
- 为了比较无症状 (CL-A) 和症状 (CL-S) 的年轻隐形眼镜使用者之间的角膜感觉神经功能.
- 为了研究眼睛表面参数的差异,如膜和温度.
主要方法:
- 使用视觉模拟尺度 (VAS) 评估角膜对机械,化学和寒冷刺激的敏感性.
- 测量了眼容量,眼破裂时间 (TBUT),眼频率 (BF) 和眼睛表面温度 (OST).
- 包括眼镜 (EG) 佩戴者作为对照.
主要成果:
- 无症状的CL使用者 (CL-A) 报告说,尽管与对照者的感官得分相似,但刺激性增加.
- 有症状的CL使用者 (CL-S) 显著减少了感冒检测能力.
- 与EG佩戴者相比,CL-A和CL-S组显示了眼频率,TBUT和OST的变化.
结论:
- 隐形眼镜的佩戴会影响年轻人的角膜敏感性,眼和动力学.
- 角膜敏感性的亚临床变化表明神经敏感性和变化的热感受.
- 角膜敏感性和OST差异可能表明不同程度的神经损伤和眼睛表面炎症.
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