Jove
Visualize
联系我们

相关概念视频

Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

3.0K
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
3.0K
Glial Cells01:04

Glial Cells

87.4K
Overview
87.4K
Neuron Structure01:30

Neuron Structure

13.0K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
13.0K
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

832
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
832

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Epigenetic mechanisms of inflammatory memory in the central nervous system.

Nature immunology·2026
Same author

Glial cells in chronic inflammation: diversity, dysfunction and therapeutic targeting.

Nature reviews. Immunology·2026
Same author

Astrocyte Functional Heterogeneity in Multiple Sclerosis.

Journal of clinical neurology (Seoul, Korea)·2026
Same author

Astrocyte-driven immunosuppression in the brain tumor microenvironment.

Nature immunology·2026
Same author

A transcriptomic microglia taxonomy across mouse and human pathologies.

Nature immunology·2026
Same author

Author Correction: Retargeted oncolytic viruses engineered to remodel the tumor microenvironment for glioblastoma immunotherapy.

Nature cancer·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jul 11, 2025

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.7K

神经炎症:一个天体细胞的视角.

Hong-Gyun Lee1, Joon-Hyuk Lee1, Lucas E Flausino1

  • 1Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Science translational medicine
|November 8, 2023
PubMed
概括

星球细胞,关键的大脑细胞,与各种神经系统细胞相互作用. 了解这些天体细胞相互作用为神经炎症和神经退行症提供了治疗潜力.

科学领域:

  • 神经科学是一个神经科学.
  • 细胞生物学 细胞生物学
  • 免疫学 免疫学 免疫学

背景情况:

  • 星球细胞是中枢神经系统 (CNS) 中的关键质细胞.
  • 它们表现出功能异质性,并与其他中枢神经系统细胞广泛相互作用.
  • 星球细胞在中枢神经系统的健康和疾病状态中都起着重要作用.

研究的目的:

  • 审查涉及天体细胞的复杂相互作用.
  • 为了探索星球细胞与居住和透的中枢神经系统细胞的交叉通话.
  • 讨论这些相互作用在神经炎症和神经退行症中的治疗含义.

主要方法:

  • 关于最近技术进步的文献综述.
  • 分析天体细胞与神经元,微质细胞,寡干细胞和免疫细胞的相互作用.
  • 综合了关于天体细胞在炎症和神经退行性疾病中的作用的数据.

主要成果:

  • 星细胞表现出不同的功能状态和信号通路.
  • 天体细胞和其他中枢神经系统细胞类型之间存在复杂的通信网络.
  • 星球细胞调节炎症反应和神经元健康.

更多相关视频

A Cell Culture Model for Studying the Role of Neuron-Glia Interactions in Ischemia
11:36

A Cell Culture Model for Studying the Role of Neuron-Glia Interactions in Ischemia

Published on: November 14, 2020

9.4K
Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
08:52

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration

Published on: January 10, 2018

14.4K

相关实验视频

Last Updated: Jul 11, 2025

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

14.7K
A Cell Culture Model for Studying the Role of Neuron-Glia Interactions in Ischemia
11:36

A Cell Culture Model for Studying the Role of Neuron-Glia Interactions in Ischemia

Published on: November 14, 2020

9.4K
Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
08:52

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration

Published on: January 10, 2018

14.4K

结论:

  • 星球细胞是中枢神经系统健康和疾病的核心参与者.
  • 准星球细胞相互作用是有前途的治疗策略.
  • 对天体细胞生物学的进一步研究可以促进神经系统疾病的治疗.